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肾脏疾病中的肺出血:古德帕斯彻综合征及其他病因。

Pulmonary hemorrhage in renal disease: Goodpasture's syndrome and other causes.

作者信息

Schwartz E E, Teplick J G, Onesti G, Schwartz A B

出版信息

Radiology. 1977 Jan;122(1):39-46. doi: 10.1148/122.1.39.

Abstract

Pulmonary hemorrhage is generally due to neoplasm, tuberculosis, necrotizing pneumonia, or bronchiectasis. If these are not found, kidney diseases, including anti-glomerular basement membrane antibody-induced bleeding (Goodpasture's syndrome), should be considered. Hemoptysis in renal disease is more often due to azotemic hypervolemia than immune reaction. Typically linear immunofluorescent patterns along the glomerular and pulmonary alveolar basement membranes must be demonstrated to confirm the diagnosis of Goodpasture's syndrome.

摘要

肺出血通常由肿瘤、肺结核、坏死性肺炎或支气管扩张引起。如果未发现这些病因,则应考虑肾脏疾病,包括抗肾小球基底膜抗体诱导的出血(古德帕斯彻综合征)。肾病中的咯血更多是由于氮质血症性血容量过多,而非免疫反应。必须证明沿肾小球和肺泡基底膜典型的线性免疫荧光模式,以确诊古德帕斯彻综合征。

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