Silverman M, Hawkins D, Ackman C F
Can Med Assoc J. 1973 Feb 3;108(3):336-40.
A case of Goodpasture's syndrome is described in which bilateral nephrectomy was undertaken because of massive pulmonary hemorrhage. Similar cases recorded in the literature are reviewed. Various hypotheses to explain the beneficial effects of renal ablation on lung purpura are considered. It is suggested that the pulmonary hemorrhage in Goodpasture's syndrome is mediated in part by a non-antibody humoral factor with permeability-increasing properties that is released from the nephritic kidney.
本文描述了一例因大量肺出血而进行双侧肾切除术的古德帕斯彻综合征病例。对文献中记载的类似病例进行了回顾。考虑了各种解释肾切除对肺紫癜有益作用的假说。有人提出,古德帕斯彻综合征中的肺出血部分是由一种具有增加通透性特性的非抗体体液因子介导的,该因子由患肾病的肾脏释放。