Nicotra M, Muttinelli C, Rolfi G, Amato P
II Istituto di Clinica Ostetrica e Ginecologica, Università La Sapienza Roma, Italia.
Acta Eur Fertil. 1993 Jan-Feb;24(1):19-21.
Abnormal cervical mucus (CM) quality and quantity is considered one of the causes of infertility which occurs in only 2 to 8 per cent of infertile couples. The periovulatory mucus with its specific properties is necessary to determine a correct Post Coital Test (PCT). Twenty patients, with infertility for over 18 months and with a baseline negative PCT (repeated at least three times) for abnormal CM, were treated with pFSH. Our results show that the pFSH improves the quality and quantity of CM in all for our patients including an improvement of penetration and motility spermatozoa in 55 per cent of our cases. Therefore we suggest the routine pFSH use in case of cervical hostility and recurrent negative PCT.
宫颈黏液（CM）的质量和数量异常被认为是不孕症的原因之一，不孕症仅发生在2%至8%的不孕夫妇中。排卵期黏液及其特定特性对于确定正确的性交后试验（PCT）至关重要。20名不孕超过18个月且因CM异常导致基线PCT阴性（至少重复三次）的患者接受了重组促卵泡素（pFSH）治疗。我们的结果表明，pFSH改善了所有患者的CM质量和数量，包括55%的病例中精子穿透率和活力的提高。因此，我们建议在宫颈因素导致不孕和反复PCT阴性的情况下常规使用pFSH。
