二氢蝶啶还原酶是一种异常的二氢叶酸还原酶、一种类黄素酶还是一种短链脱氢酶？ - Suppr

Suppr

超能文献

Is dihydropteridine reductase an anomalous dihydrofolate reductase, a flavin-like enzyme, or a short-chain dehydrogenase?

作者信息

Whiteley J M, Xuong N H, Varughese K I

机构信息

Scripps Research Institute, La Jolla, CA 92037.

出版信息

Adv Exp Med Biol. 1993;338:115-21. doi: 10.1007/978-1-4615-2960-6_23.

DOI:10.1007/978-1-4615-2960-6_23

PMID:8304093

Abstract

摘要

相似文献

Is dihydropteridine reductase an anomalous dihydrofolate reductase, a flavin-like enzyme, or a short-chain dehydrogenase?二氢蝶啶还原酶是一种异常的二氢叶酸还原酶、一种类黄素酶还是一种短链脱氢酶？

Adv Exp Med Biol. 1993;338:115-21. doi: 10.1007/978-1-4615-2960-6_23.

Comparative properties of three pteridine reductases.三种蝶啶还原酶的比较特性

Adv Exp Med Biol. 1999;463:403-10. doi: 10.1007/978-1-4615-4735-8_50.

Dihydropteridine reductase from Escherichia coli exhibits dihydrofolate reductase activity.来自大肠杆菌的二氢蝶啶还原酶具有二氢叶酸还原酶活性。

Biol Chem Hoppe Seyler. 1992 Oct;373(10):1067-73. doi: 10.1515/bchm3.1992.373.2.1067.

Eukaryotic dihydrofolate reductase.真核生物二氢叶酸还原酶

Adv Enzymol Relat Areas Mol Biol. 1995;70:23-102. doi: 10.1002/9780470123164.ch2.

Dihydropteridine reductase as an alternative to dihydrofolate reductase for synthesis of tetrahydrofolate in Thermus thermophilus.嗜热栖热菌中二氢蝶啶还原酶作为二氢叶酸还原酶用于合成四氢叶酸的替代物。

J Bacteriol. 2004 Jan;186(2):351-5. doi: 10.1128/JB.186.2.351-355.2004.

Pteridine reductase mechanism correlates pterin metabolism with drug resistance in trypanosomatid parasites.蝶啶还原酶机制将锥虫寄生虫中的蝶呤代谢与耐药性联系起来。

Nat Struct Biol. 2001 Jun;8(6):521-5. doi: 10.1038/88584.

Structural and mechanistic implications of incorporating naturally occurring aberrant mutations of human dihydropteridine reductase into a rat model.将人类二氢蝶啶还原酶的天然异常突变纳入大鼠模型的结构和机制意义。

Int J Pept Protein Res. 1994 Sep;44(3):278-87. doi: 10.1111/j.1399-3011.1994.tb00171.x.

Structural and mechanistic characteristics of dihydropteridine reductase: a member of the Tyr-(Xaa)3-Lys-containing family of reductases and dehydrogenases.二氢蝶啶还原酶的结构和机制特征：含Tyr-(Xaa)3-Lys还原酶和脱氢酶家族的成员

Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5582-6. doi: 10.1073/pnas.91.12.5582.

Does R67 dihydrofolate reductase possess a proton donor?R67二氢叶酸还原酶是否拥有质子供体？

Adv Exp Med Biol. 1993;338:493-8. doi: 10.1007/978-1-4615-2960-6_99.

Three sisters, different names.三姐妹，名字各异。

Nat Struct Biol. 1994 Mar;1(3):146-7. doi: 10.1038/nsb0394-146.

引用本文的文献

Homology modelling, molecular docking, and molecular dynamics simulations reveal the inhibition of Leishmania donovani dihydrofolate reductase-thymidylate synthase enzyme by Withaferin-A.同源性建模、分子对接和分子动力学模拟揭示了 Withaferin-A 对杜氏利什曼原虫二氢叶酸还原酶-胸苷酸合成酶的抑制作用。

BMC Res Notes. 2018 Apr 16;11(1):246. doi: 10.1186/s13104-018-3354-1.

Gene regulation of pteridine reductase 1 in leishmania promastigotes and amastigotes using a full-length antisense construct.利用全长反义构建体对利什曼原虫前鞭毛体和无鞭毛体中蝶啶还原酶1的基因调控

Iran J Parasitol. 2013 Apr;8(2):190-6.

PTR1: a reductase mediating salvage of oxidized pteridines and methotrexate resistance in the protozoan parasite Leishmania major.PTR1：一种还原酶，介导原生动物寄生虫硕大利什曼原虫中氧化蝶啶的补救和甲氨蝶呤抗性。

Proc Natl Acad Sci U S A. 1994 Nov 22;91(24):11442-6. doi: 10.1073/pnas.91.24.11442.

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