真核生物二氢叶酸还原酶 - Suppr

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超能文献

Eukaryotic dihydrofolate reductase.

作者信息

Blakley R L

机构信息

Department of Molecular Pharmacology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

出版信息

Adv Enzymol Relat Areas Mol Biol. 1995;70:23-102. doi: 10.1002/9780470123164.ch2.

DOI:10.1002/9780470123164.ch2

PMID:8638484

Abstract

摘要

相似文献

Eukaryotic dihydrofolate reductase.真核生物二氢叶酸还原酶

Adv Enzymol Relat Areas Mol Biol. 1995;70:23-102. doi: 10.1002/9780470123164.ch2.

Comparison of binding and activity of 8-alkyl-pterins and 8-alkyl-N5-deaza-pterins with dihydrofolate reductase.8-烷基蝶呤和8-烷基-N5-脱氮蝶呤与二氢叶酸还原酶的结合及活性比较

Adv Exp Med Biol. 1993;338:525-8. doi: 10.1007/978-1-4615-2960-6_106.

Effect of codon 22 mutations on substrate and inhibitor binding for human dihydrofolate reductase.密码子22突变对人二氢叶酸还原酶底物和抑制剂结合的影响。

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Is dihydropteridine reductase an anomalous dihydrofolate reductase, a flavin-like enzyme, or a short-chain dehydrogenase?二氢蝶啶还原酶是一种异常的二氢叶酸还原酶、一种类黄素酶还是一种短链脱氢酶？

Adv Exp Med Biol. 1993;338:115-21. doi: 10.1007/978-1-4615-2960-6_23.

The crystal structure of dihydrofolate reductase from Thermotoga maritima: molecular features of thermostability.嗜热栖热菌二氢叶酸还原酶的晶体结构：热稳定性的分子特征

J Mol Biol. 2000 Mar 31;297(3):659-72. doi: 10.1006/jmbi.2000.3570.

The effect of codon 31 on the relative affinities for the binding of designed 8-alkyl-pterins to dihydrofolate reductase: a statistical perturbation theory and molecular dynamics simulation study.密码子31对设计的8-烷基蝶呤与二氢叶酸还原酶结合相对亲和力的影响：统计微扰理论与分子动力学模拟研究

Adv Exp Med Biol. 1993;338:511-4. doi: 10.1007/978-1-4615-2960-6_103.

Dihydrofolate reductase: a potential drug target in trypanosomes and leishmania.二氢叶酸还原酶：锥虫和利什曼原虫中的一个潜在药物靶点。

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Active site-directed double mutants of dihydrofolate reductase.二氢叶酸还原酶的活性位点定向双突变体

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Structure of and kinetic channelling in bifunctional dihydrofolate reductase-thymidylate synthase.双功能二氢叶酸还原酶-胸苷酸合成酶的结构与动力学通道

Nat Struct Biol. 1994 Mar;1(3):186-94. doi: 10.1038/nsb0394-186.

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