Determinants of the disparate antitumor effects of (6R)5,10-dideaza-5,6,7,8- tetrahydrofolate and methotrexate toward methotrexate resistant CCRF-CEM cells, characterized by severely impaired antifolate membrane transport.

Matherly L H, Angeles S M

Development Therapeutics Program, Michigan Cancer Foundation, Detroit 48201.

Adv Exp Med Biol. 1993;338:783-6. doi: 10.1007/978-1-4615-2960-6_164.

Abstract

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