Kleid J J, Arvan S B, Martin C
Chest. 1977 Jan;71(1):65-9. doi: 10.1378/chest.71.1.65.
Left ventricular function, as measured by systolic time intervals, was studied in 30 subjects with the syndrome of midsystolic click and late systolic murmur (ages, 20 to 53 years; mean, 34 +/- 9 years). Twenty-one were asymptomatic, six had chest pain, two had palpitations, one had shortness of breath, and one had hypotensive episodes. Each patient had the typical auscultatory and echocardiographic findings of the syndrome of midsystolic click and late systolic murmur. In the study the values for the interval between the onset of the QRS complex (Q) and the aortic component of the second heart sound (A2) (377 +/- 42 msec), the Q-A2 index (532 +/- 39 msec), the preejection period (PEP) (97 +/- 17 MSEC), THE PEP index (127 +/- 16 msec), the left ventricular ejection time index (403 +/- 26 msec) and the ratio of PEP to left ventricular ejection time (0.35 +/- 0.01) were not significantly different from the values in 17 controls matched for age. Out study, then, supports the contention that left ventricular function remains well preserved in most patients with the syndrome of midsystolic click and late systolic murmur.
采用收缩期时间间期测量左心室功能，对30例伴有收缩中期喀喇音和收缩晚期杂音综合征的患者（年龄20至53岁，平均34±9岁）进行了研究。其中21例无症状，6例有胸痛，2例有心悸，1例有气短，1例有低血压发作。每位患者均有收缩中期喀喇音和收缩晚期杂音综合征的典型听诊及超声心动图表现。在本研究中，QRS波群起始（Q）至第二心音主动脉成分（A2）的间期值（377±42毫秒）、Q - A2指数（532±39毫秒）、射血前期（PEP）（97±17毫秒）、PEP指数（127±16毫秒）、左心室射血时间指数（403±26毫秒）以及PEP与左心室射血时间的比值（0.35±0.01）与17名年龄匹配的对照组的值相比，差异无统计学意义。因此，我们的研究支持这样的观点，即大多数伴有收缩中期喀喇音和收缩晚期杂音综合征的患者左心室功能仍保持良好。
