Wilske J
Department of Nephrology, Sahlgrenska sjukhuset, Gothenburg, Sweden.
Arctic Med Res. 1993 Oct;52(4):166-9.
Vitamin D3 is produced in the skin of animals and humans by the sun's ultraviolet rays (UVB region, 290-315 nm). The main metabolite 25-hydroxyvitamin-D3 has a seasonal variation, depending on the ultraviolet radiation. In the Antarctic preliminary investigations on penguins (Pygoscelis papua), female sea elephants (Mirounga leonina), and humans showed that there was an increase in plasma 25-hydroxyvitamin-D3 concentrations during UV-exposure in all three species. This metabolite can therefore be regarded as a molecular indicator of UV radiation. The possibility to use this compound in a long term monitoring program, for UV radiation, is under investigation.
维生素D3由太阳紫外线（UVB区域，290 - 315纳米）在动物和人类皮肤中产生。主要代谢产物25 - 羟基维生素D3存在季节性变化，这取决于紫外线辐射。在南极对巴布亚企鹅（Pygoscelis papua）、雌性海象（Mirounga leonina）和人类进行的初步调查表明，在紫外线照射期间，这三个物种的血浆25 - 羟基维生素D3浓度均有所增加。因此，这种代谢产物可被视为紫外线辐射的分子指标。目前正在研究将该化合物用于紫外线辐射长期监测项目的可能性。
