Murphy N J, Boyko E J, Schraer C D, Bulkow L R, Lanier A P
Alaska Native Health Service, Bethel.
Arctic Med Res. 1993 Oct;52(4):170-4.
Investigate the Accu-Chek II and visual Chemstrip bG methods for non-insulin dependent diabetes mellitus (NIDDM) screening under field conditions with the aid of local providers.
Compare simultaneous random Chemstrip bG, Accu-Chek II and plasma glucose levels using a 6.7 mM cut-off, followed by a 75 gram 2 hour oral glucose tolerance test while screening 1124 people in 15 Alaskan villages with the aid of local personnel during winter field conditions.
The Accu-Chek II and visual Chemstrip bG methods detected 92% and 96%, respectively, of those newly diagnosed with NIDDM whose plasma screen was > or = 6.7 mM. The Accu-Chek II provided correlations of 0.774, 0.850, 0.923, and 0.946 with random, fasting, 1 and 2 hour plasma glucose. The mean Accu-Chek II, Chemstrip bG and plasma levels at which NIDDM was diagnosed were not statistically different. Receiver operator characteristic (ROC) curve analysis revealed optimum screening cut-off values for subsequent new diagnosis of NIDDM to be 8.3, 7.7, and 8.0 mM for visual, Accu-Chek II and hexokinase methods (p = NS).
The Accu-Chek II and Chemstrip bG provided accurate glucose data in random NIDDM screening under field conditions with multiple local providers.
在当地医疗人员的协助下，研究在现场条件下使用罗氏卓越型血糖仪（Accu-Chek II）和尿糖试纸（visual Chemstrip bG）进行非胰岛素依赖型糖尿病（NIDDM）筛查的情况。
在冬季现场条件下，借助当地人员对阿拉斯加15个村庄的1124人进行筛查，同时使用6.7 mM的临界值比较随机尿糖试纸法、罗氏卓越型血糖仪法和血浆葡萄糖水平，随后进行75克2小时口服葡萄糖耐量试验。
罗氏卓越型血糖仪法和尿糖试纸法分别检测出那些血浆筛查值≥6.7 mM且新诊断为NIDDM患者中的92%和96%。罗氏卓越型血糖仪法与随机、空腹、1小时和2小时血浆葡萄糖的相关性分别为0.774、0.850、0.923和0.946。诊断NIDDM时罗氏卓越型血糖仪法、尿糖试纸法和血浆水平的平均值无统计学差异。受试者工作特征（ROC）曲线分析显示，对于后续新诊断NIDDM，尿糖试纸法、罗氏卓越型血糖仪法和己糖激酶法的最佳筛查临界值分别为8.3、7.7和8.0 mM（p = 无显著性差异）。
在现场条件下，由多名当地医疗人员参与使用罗氏卓越型血糖仪法和尿糖试纸法进行随机NIDDM筛查时，可提供准确的血糖数据。
