[胆碱酯酶抑制剂在阿尔茨海默病中的应用]
[Use of cholinesterase inhibitors in Alzheimer disease].
作者信息
Sampalmieri M, Troiani M P, Servi M
机构信息
II Divisione di Geriatria, Ospedale dell'Addolorata di Roma.
出版信息
Clin Ter. 1993 Dec;143(6):549-52.
PMID:8306579
Abstract
According to the cholinergic theory of Alzheimer's disease, the cognitive failure depends on a deficit in acetylcholine. The study reported above examines the efficacy and tolerability of cholinesterase inhibitors, such as tetrahydroamino acridine (THA), for the management of this pathology.
摘要
根据阿尔茨海默病的胆碱能理论，认知功能衰退取决于乙酰胆碱缺乏。上述研究考察了胆碱酯酶抑制剂（如四氢氨基吖啶，THA）治疗该疾病的疗效和耐受性。
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