Fujita J, Yamadori I, Yamaji Y, Yamagishi Y, Takigawa K, Takahara J
First Department of Internal Medicine, Kagawa Medical School, Japan.
Chest. 1994 Feb;105(2):624-5. doi: 10.1378/chest.105.2.624.
A 49-year-old man complained of a 3-month history of progressive generalized muscle weakness. He was diagnosed as having small-cell lung carcinoma at the same time. He received an intravenous injection of edrophonium chloride with remarkable improvement of muscle strength. Electromyographic studies revealed a compound muscle action potential that decreased after repetitive stimulation. These findings were considered representative of myasthenia gravis (MG), and inconsistent with Eaton-Lambert syndrome. The appearance of MG with small-cell lung carcinoma seems to be very rare, but possible.
一名49岁男性主诉有3个月进行性全身肌无力病史。他同时被诊断为小细胞肺癌。他接受了氯化依酚氯铵静脉注射，肌力有显著改善。肌电图研究显示重复刺激后复合肌肉动作电位降低。这些发现被认为是重症肌无力（MG）的典型表现，与伊顿-兰伯特综合征不符。小细胞肺癌合并重症肌无力的情况似乎非常罕见，但有可能发生。
