Tuikka R A, Laaksonen R K, Somer H V
Department of Neurology, University of Helsinki, Finland.
Eur Neurol. 1993;33(6):436-41. doi: 10.1159/000116989.
Intellectual and cognitive function were studied in 35 patients with myotonic dystrophy (DM). All 5 patients with the congenital form showed moderate or mild mental retardation. The 30 adult-onset patients had normal intelligence and memory quotients. In this adult-onset group no differences in cognitive function were observed either with respect to sex or physical disability. The sex of the affected parent, mother vs. father, was also without effect in this group. A follow-up study was performed in 16 patients with a mean test interval of 12 years. There was no severe cognitive impairment over this time span or a significant correlation between the progression of physical and cognitive dysfunction.
对35例强直性肌营养不良（DM）患者的智力和认知功能进行了研究。所有5例先天性患者均表现为中度或轻度智力发育迟缓。30例成年发病患者的智力和记忆商数正常。在这个成年发病组中，无论是性别还是身体残疾，认知功能均未观察到差异。受影响父母的性别，母亲与父亲，在该组中也没有影响。对16例患者进行了随访研究，平均测试间隔为12年。在此时间段内没有严重的认知障碍，身体和认知功能障碍的进展之间也没有显著相关性。
