Molin L
Acta Derm Venereol. 1975;55(2):151-3.
The phagocytic ability of neutrophil leucocytes was found to be impaired in patients suffering from pustulosis palmaris et plantaris (PPP). This ability was studied with the aid of the yeast particle method. In 78% of 27 patients whose PPP was in a static phase, the phagocytic function was enhanced, while the PPP abated concomitantly and the pustules disappeared. Impaired phagocytosis and the beneficial effect of clofazimine signify the pathogenic importance of defective neutrophils in PPP.
研究发现，掌跖脓疱病（PPP）患者的中性粒细胞吞噬能力受损。采用酵母颗粒法对这种能力进行了研究。在27例处于静止期的掌跖脓疱病患者中，78%的患者吞噬功能增强，同时掌跖脓疱病病情减轻，脓疱消失。吞噬作用受损以及氯法齐明的有益作用表明中性粒细胞缺陷在掌跖脓疱病发病机制中的重要性。
