Khomeriki S G, Kubatiev A A, Shliapnikov V N
Gematol Transfuziol. 1993 Jul-Aug;38(7):26-8.
To clarify the changes in cellular reactivity in response to single irradiation of blood with He-Ne laser, the authors studied neutrophil aggregation and neutrophil ATP release induced by stimulation with lectins diverse in carbohydrate specificity. Blood samples from 30 healthy donors were investigated using PICA lumoaggregometer (Chrono-Log Corporation, USA) and concanavalin A, PHA-L, WGA, SBA as aggregation inductors. He-Ne laser radiation in most cases results in reduced neutrophil capacity for aggregation. Nevertheless, it activates ATP release under stimulation with lectins of various carbohydrate specificity. It follows that mechanisms of lectin-induced reactions, aggregation of neutrophils and ATP release, are different.
为了阐明血液单次接受氦氖激光照射后细胞反应性的变化，作者研究了不同碳水化合物特异性的凝集素刺激诱导的中性粒细胞聚集和中性粒细胞ATP释放。使用PICA lumoaggregometer（美国Chrono-Log公司）以及伴刀豆球蛋白A、PHA-L、WGA、SBA作为聚集诱导剂，对30名健康供体的血样进行了研究。在大多数情况下，氦氖激光辐射会导致中性粒细胞聚集能力下降。然而，它会在不同碳水化合物特异性的凝集素刺激下激活ATP释放。由此可见，凝集素诱导反应、中性粒细胞聚集和ATP释放的机制是不同的。
