Sitnikova T L, Zharkikh A A
Genetika. 1993 Nov;29(11):1793-805.
Mitochondrial-like sequences and their homologues from primate mitochondria are investigated to define direction and rate of evolution, time of integration into nuclear genome. The analysis showed that mito-like sequences differ from mitochondrial homologues by high level of symmetria of two chains of DNA. Besides that, difference between mito-like and Homo sapiens sequences in their GC-contents is found. Apparently there is GC-pressure of nuclear genome region, being the place of integration of mito-like sequence, that brings about equalization of GC-contents in nuclear region and mito-like sequences. Properties of descent mitochondrial sequence play important role in the difference of mito-like and Homo sapiens sequences also.
对来自灵长类动物线粒体的类线粒体序列及其同源物进行了研究，以确定进化方向和速率、整合到核基因组中的时间。分析表明，类线粒体序列与线粒体同源物的区别在于DNA两条链的对称性较高。除此之外，还发现了类线粒体序列与智人序列在GC含量上的差异。显然，作为类线粒体序列整合位点的核基因组区域存在GC压力，这导致了核区域和类线粒体序列中GC含量的均衡。祖先线粒体序列的特性在类线粒体序列与智人序列的差异中也起着重要作用。
