Salzmann E, Wiedemann O, Löffler L, Sperber H
Sanofi-Winthrop GmbH, Medizinische Abteilung, München.
Fortschr Med. 1993 Dec 10;111(34):544-8.
In a double-blind study, 20 ambulatory patients with acute painful restriction of mobility of the cervical spine and overall marked impairment were treated for seven days with tetrazepam (150 mg or a lower dose from the third day onward) or placebo. Paracetamol was permitted in addition if required. Test criteria: The main criterion of efficacy was a summed score of three parameters: pain, restriction of mobility, and general impairment.
The difference between the groups was statistically highly significant (p = 0.005). Tolerability was adjudged to be "very good" for the placebo group, and, on average, "good" for the tetrazepam group.
在一项双盲研究中，20名患有急性颈椎活动受限且整体明显受损的门诊患者接受了为期7天的替马西泮（150毫克，从第三天起剂量降低）或安慰剂治疗。如有需要，可额外使用对乙酰氨基酚。测试标准：疗效的主要标准是三个参数的总分：疼痛、活动受限和整体受损情况。
两组之间的差异具有高度统计学意义（p = 0.005）。安慰剂组的耐受性被判定为“非常好”，替马西泮组平均为“好”。
