Zuccaro G
Department of Gastroenterology, Cleveland Clinic Foundation, Ohio.
Gastroenterol Clin North Am. 1993 Dec;22(4):737-50.
The presence of stigmata of hemorrhage in a peptic ulcer indicate an increased risk of rebleeding and the need for endoscopic intervention. Clinical trials indicate that laser photocoagulation, multipolar and heater probe coagulation, and injection therapy are all effective in decreasing bleeding from peptic ulcer disease. The modality used for the individual patient depends on available resources and the experience of the endoscopist. Laser photocoagulation is used infrequently, not because of a lack of efficacy but because of its increased cost and impracticality, including its lack of portability. Multipolar coagulation and heater probe coagulation are commonly employed but may give way to injection therapy as first-line therapy, because it is equally effective, cost less, and is easy to implement in a variety of clinical settings.
消化性溃疡出现出血迹象表明再出血风险增加，需要进行内镜干预。临床试验表明，激光光凝、多极和热探头凝固以及注射疗法在减少消化性溃疡疾病出血方面均有效。针对个体患者所使用的治疗方式取决于可用资源和内镜医师的经验。激光光凝很少使用，并非因为缺乏疗效，而是因其成本增加且不实用，包括缺乏便携性。多极凝固和热探头凝固是常用的，但可能会被注射疗法取代作为一线治疗方法，因为它同样有效、成本更低，并且易于在各种临床环境中实施。
