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[一例新生儿重症主动脉瓣狭窄成功实施开放性瓣膜切开术的病例报告]

[A case report of successful open valvotomy in neonate with critical aortic stenosis].

作者信息

Hosokawa Y, Chibana M, Nakama T, Takara Y, Ganaha H

机构信息

Department of Cardiovascular Surgery, Naha General Hospital, Okinawa, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1994 Jan;42(1):126-31.

PMID:8308370
Abstract

Open valvotomy was successfully performed in neonate with critical aortic stenosis using cardiopulmonary bypass. The baby was referred to our hospital at the age of 24 days with very grave state, and needed intensive care including endotracheal intubation and inotropic support. Critical valvular aortic stenosis was confirmed by echocardiography. Poststenotic dilatation and enough size of short axis LV dimension were reported, and aortic annulus was measured 6 mm in diameter. Without catheterization and angiography, open valvotomy was performed with moderate hypothermia and ischemic arrest using single dose of cold cardioplegia at the age of 29 days. Bicuspid aortic valve was thick and dysplastic with thick gelatinous cusp edge, however commissurotomy was applicable in two direction. The diameter of aortic opening was enlarged from 2 mm to 7 mm. Total bypass and aortic cross clamp time were 78 and 28 minutes respectively. The baby recovered uneventfully and there was no evidence of significant AS or aortic regurgitation in echocardiography 7 months after surgery. Sorts of reoperation for restenosis or regurgitation were reported. The results of reoperation for regurgitation were reported to be poor, especially in young infants who should be performed aortic valve replacement. However, residual AS could be manipulated with re-valvotomy, PVB, apico-aortic conduit or AVR. As the choice of first relief of critical AS without other anatomical disadvantages including hypoplastic left ventricle, endocardial fibroelastosis, and mitral stenosis, it would be crucial for late results to prevent progression of aortic regurgitation.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在一名患有严重主动脉瓣狭窄的新生儿中,采用体外循环成功实施了开放性瓣膜切开术。该婴儿24天时因病情极为严重被转诊至我院,需要包括气管插管和使用血管活性药物支持在内的重症监护。经超声心动图确诊为严重瓣膜性主动脉狭窄。报告显示有狭窄后扩张且左心室短轴尺寸足够大,测量主动脉瓣环直径为6毫米。在未进行心导管检查和血管造影的情况下,于29天时采用中度低温和缺血性停搏,单次给予冷心脏停搏液,实施了开放性瓣膜切开术。二叶式主动脉瓣增厚且发育异常,瓣叶边缘呈厚胶冻状,但可在两个方向进行交界切开术。主动脉开口直径从2毫米扩大至7毫米。体外循环总时间和主动脉阻断时间分别为78分钟和28分钟。术后婴儿恢复顺利,术后7个月超声心动图检查未发现明显主动脉狭窄或主动脉反流迹象。报道了因再狭窄或反流进行的各类再次手术情况。据报道,因反流进行再次手术的效果不佳,尤其是对于应行主动脉瓣置换术的幼儿。然而,残余主动脉狭窄可通过再次瓣膜切开术、经皮球囊瓣膜成形术、心尖 - 主动脉管道或主动脉瓣置换术进行处理。作为在不存在其他解剖学不利因素(包括左心室发育不全、心内膜弹力纤维增生症和二尖瓣狭窄)的情况下对严重主动脉狭窄进行首次缓解的选择,预防主动脉反流进展对于远期结果至关重要。(摘要截选至250词)

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