Ramsey J M, Salinas E, Rodriguez M H, Beaudoin R L
Centro de Investigacion de Paludismo, SSA/OPS, Tapachula, Chiapas, Mexico.
J Parasitol. 1994 Feb;80(1):88-92.
Two colonized populations of Anopheles albimanus isolated from the Suchiate region, Chiapas State, Mexico, were compared for their susceptibility to coindigenous Plasmodium vivax. Groups of mosquitoes were fed in vitro with either autologous donor blood or the same blood cells substituted with serum negative for anti-gametocyte antibody. Significant differences in susceptibility between the 2 colonies were encountered if the autologous blood from a patient was fed to mosquitoes: mean infection rates of AnA2-positive groups was double that in AnA1 mosquitoes. Consistent for both colonies, only 23.6% of samples positive from malaria-negative serum-substituted blood were infected with an autologous blood feed. Vector competence in these mosquito populations was partially linked to the human populations's immune response to the parasite.
对从墨西哥恰帕斯州苏奇亚特地区分离出的两个白纹按蚊定殖种群，就其对当地间日疟原虫的易感性进行了比较。将蚊群在体外用自体供血者血液或用抗配子体抗体阴性的血清替代相同血细胞的血液喂养。如果将患者的自体血液喂给蚊子，两个蚊群之间的易感性存在显著差异：AnA2阳性组的平均感染率是AnA1蚊子的两倍。两个蚊群的情况一致，用疟疾阴性血清替代血液的样本中，只有23.6%在喂以自体血液后被感染。这些蚊群的媒介能力部分与人群对寄生虫的免疫反应有关。
