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墨西哥南部白纹按蚊和伪点按蚊对本地间日疟原虫变种VK210和VK247感染的易感性差异

Differential susceptibilities of Anopheles albimanus and Anopheles pseudopunctipennis to infections with coindigenous Plasmodium vivax variants VK210 and VK247 in southern Mexico.

作者信息

Gonzalez-Ceron L, Rodriguez M H, Nettel J C, Villarreal C, Kain K C, Hernandez J E

机构信息

Centro de Investigación de Paludismo, Instituto Nacional de Salud Publica, Cuernavaca, Morelos, Mexico.

出版信息

Infect Immun. 1999 Jan;67(1):410-2. doi: 10.1128/IAI.67.1.410-412.1999.

Abstract

The susceptibilities to coindigenous Plasmodium vivax of colonized Anopheles albimanus and Anopheles pseudopunctipennis from southern Mexico were investigated by simultaneous feeding with infected blood obtained from patients. The genes encoding circumsporozoite protein variant types (VK210 and VK247) in blood samples were determined by PCR and oligonucleotide probe hybridization. A. albimanus was more susceptible to VK210, and A. pseudopunctipennis was more susceptible to VK247.

摘要

通过用从患者身上获取的感染血液同时喂食,对来自墨西哥南部的定殖白纹按蚊和伪点按蚊对间日疟原虫的易感性进行了研究。通过聚合酶链反应(PCR)和寡核苷酸探针杂交测定血样中编码环子孢子蛋白变异类型(VK210和VK247)的基因。白纹按蚊对VK210更易感,而伪点按蚊对VK247更易感。

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