Walton J M, Rubin S Z, Soucy P, Benzie R, Ash K, Nimrod C
Department of Surgery, Children's Hospital of Eastern Ontario, Ottawa, Canada.
J Pediatr Surg. 1993 Sep;28(9):1151-3. doi: 10.1016/0022-3468(93)90152-b.
Fetal tumors are being diagnosed with increasing frequency and great accuracy by antenatal ultrasound. High-output cardiac failure and hydrops indicate fetal distress. Management may be limited by the gestational age of the fetus. Our experience with three fetal tumors demonstrates the dilemma with respect to timing of delivery and prognosis. Following the diagnosis of a large sacrococcygeal tumor, a 22-week-gestation fetus became hydropic and died. Another fetus with a rapidly growing posterolateral chest wall mass required cesarean section delivery at 29 weeks gestation. Postnatal course was complicated by pulmonary hypoplasia, intratumoral hemorrhage, and death. The third fetus had an enlarging tumor in the right lobe of the liver. Poor biophysical profile and mild hydrops necessitated cesarean section delivery at 34 weeks. Right hepatic lobectomy was performed and the infant was subsequently discharged home at one month of age. The deleterious effects of the fetal tumor and the need for its removal have to be carefully weighed against the ability of the fetus to survive postnatally.
产前超声诊断胎儿肿瘤的频率越来越高,准确性也越来越高。高输出量心力衰竭和水肿提示胎儿窘迫。治疗可能会受到胎儿孕周的限制。我们对三例胎儿肿瘤的经验表明了在分娩时机和预后方面的困境。诊断出巨大的骶尾部肿瘤后,一名孕22周的胎儿出现水肿并死亡。另一名孕29周时后外侧胸壁肿块迅速生长的胎儿需要剖宫产分娩。产后病程因肺发育不全、肿瘤内出血和死亡而复杂化。第三名胎儿肝脏右叶有一个不断增大的肿瘤。生物物理评分差和轻度水肿使得在孕34周时必须剖宫产分娩。进行了右肝叶切除术,婴儿随后在1月龄时出院回家。必须仔细权衡胎儿肿瘤的有害影响及其切除的必要性与胎儿出生后存活的能力。