Abell T L, Merigian K S, Lee J M, Holbert J M, McCall J W
University of Tennessee, Memphis.
J Toxicol Clin Toxicol. 1994;32(1):69-73. doi: 10.3109/15563659409000432.
A case of intercerebral hematoma due to warfarin-induced coagulopathy is presented. The 39-year-old woman had spread a warfarin-type rat poison around her house weekly using her bare hands, with no washing post application. Percutaneous absorption of warfarin causing coagulopathy, reported three times in the past, is a significant risk if protective measures, such as gloves, are not used. An adverse drug interaction with piroxicam, which she took occasionally, may have exacerbated the coagulopathy.
本文报告一例因华法林所致凝血病引起的脑内血肿病例。该39岁女性每周徒手在其房屋周围撒布华法林类灭鼠药，撒药后不洗手。经皮吸收华法林导致凝血病，过去已有三次报道，如果不采取如戴手套等保护措施，会有很大风险。她偶尔服用的吡罗昔康与之发生的药物不良相互作用可能加剧了凝血病。
