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通过肾盂肾盂造口术挽救伴有输尿管远端并发症的肾移植。

Rescue of renal transplants with distal ureteral complications by pyelo-pyelostomy.

作者信息

Wagner M, Dieckmann K P, Klän R, Fielder U, Offermann G

机构信息

Urologische Klinik, Klinikum Steglitz, Freie Universität Berlin, Germany.

出版信息

J Urol. 1994 Mar;151(3):578-81. doi: 10.1016/s0022-5347(17)35019-x.

Abstract

Secondary ureteroneocystostomy is the procedure most commonly used for repair of ureteral stenosis or necrosis in renal transplant patients. However, when the transplant ureter available for reconstruction is too short, ureteropyelostomy is the standard procedure. Another option is pyelo-pyelostomy, which has been used infrequently to date. Between 1979 and 1988 we managed 6 patients (4 men and 2 women 42 to 62 years old) with renal allografts who required repair of the transplant ureter for long segmented ureteral necrosis (3), long segmented ureteral stenosis (2) and an iatrogenic lesion of the ureter (1) with pyelo-pyelostomy. Of the 6 patients 2 had undergone previous rescue operations. Pyelo-pyelostomy with the renal pelvis of the graft was performed as first described by Gil-Vernet and Caralps in 1968. Median followup was 6 years (range 3 to 12 years). Two patients died of chronic rejection and pulmonary embolism, respectively. Four patients are still alive with functioning transplants and serum creatinine levels of less than 210 mumol/l. According to our experiences with 6 patients, we believe that pyelo-pyelostomy is a promising rescue maneuver that is worth consideration in cases of total or subtotal ureteral necrosis and long segmented ureteral stenosis after renal transplantation.

摘要

二期输尿管膀胱吻合术是肾移植患者输尿管狭窄或坏死修复最常用的术式。然而,当可用于重建的移植输尿管过短时,输尿管肾盂吻合术则是标准术式。另一种选择是肾盂-肾盂吻合术,目前应用较少。1979年至1988年间,我们采用肾盂-肾盂吻合术治疗了6例(4例男性,2例女性,年龄42至62岁)同种异体肾移植患者,这些患者因长节段输尿管坏死(3例)、长节段输尿管狭窄(2例)和医源性输尿管损伤(1例)而需要修复移植输尿管。6例患者中有2例曾接受过挽救性手术。肾盂-肾盂吻合术按照1968年吉尔-韦尔内和卡拉尔斯首次描述的方法进行,将移植肾肾盂进行吻合。中位随访时间为6年(范围3至12年)。2例患者分别死于慢性排斥反应和肺栓塞。4例患者移植肾功能良好,血清肌酐水平低于210μmol/L,仍然存活。根据我们对6例患者的经验,我们认为肾盂-肾盂吻合术是一种有前景的挽救性手术,在肾移植后输尿管完全或部分坏死以及长节段输尿管狭窄的病例中值得考虑。

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