Attia Romdhane N, Ben Hamida M, Mrabet A, Larnaout A, Samoud S, Ben Hamda A, Ben Hamda M, Oueslati S
Institut National de Neurologie, La Rabta, Tunis, Tunisia.
Neuroepidemiology. 1993;12(5):285-99. doi: 10.1159/000110330.
A full-scale survey, in Kelibia, Tunisia, screening 34,874 persons started on July 1, 1985. The accuracy of this survey was evaluated by a second survey using a randomized sample of 1,673 subjects (control survey). Better selection and training of the interviewers during the control survey led to a higher positive predictive value with no modification in prevalence ratios of neurologic disorders. The control survey helped to validate the full-scale survey data which were then used to establish the prevalence ratios of major neurologic disorders in Kelibia. Prevalence ratios, age-adjusted to the WHO population, were compared to those of studies using similar methodology. Migraine prevalence ratios in Nigeria, Ecuador, and Kelibia were equivalent. Epilepsy and Parkinson's disease prevalence ratios were close to those of other similar studies. The stroke prevalence ratio was low, compared to other studies, but was not the lowest. It seems that in Kelibia, stroke does not constitute a public health problem as it does in the USA or urban China. The large full-scale survey, in Kelibia, provided estimates of prevalence ratios for stroke, epilepsy, migraine and other common neurologic disorders for comparisons with other countries. However, definitions of neurologic disorders and diagnostic criteria differ from one study to another making difficult the comparison of results between different countries. Had the WHO protocol developed well-defined criteria and a standardized neurologic examining tool, more accurate comparisons could have been made.
1985年7月1日，在突尼斯的凯利比亚开始了一项全面调查，对34,874人进行筛查。通过对1,673名受试者的随机样本进行第二次调查（对照调查）来评估此次调查的准确性。在对照调查期间，对访谈员进行了更好的选拔和培训，从而提高了阳性预测值，而神经系统疾病的患病率没有改变。对照调查有助于验证全面调查数据，这些数据随后被用于确定凯利比亚主要神经系统疾病的患病率。将根据世界卫生组织人群进行年龄调整后的患病率与使用类似方法的研究的患病率进行比较。尼日利亚、厄瓜多尔和凯利比亚的偏头痛患病率相当。癫痫和帕金森病的患病率与其他类似研究相近。与其他研究相比，中风的患病率较低，但不是最低的。在凯利比亚，中风似乎不像在美国或中国城市那样构成公共卫生问题。在凯利比亚进行的大规模全面调查提供了中风癫痫、偏头痛和其他常见神经系统疾病的患病率估计值，以便与其他国家进行比较。然而，不同研究对神经系统疾病的定义和诊断标准各不相同，这使得不同国家之间的结果比较变得困难。如果世界卫生组织的方案制定了明确的标准和标准化的神经系统检查工具，就可以进行更准确的比较。
