Nardini A, Falco E, Celoria G, Neviani A L, Stefani R, Gadducci G, Astesana L, Spinetta G
II Divisione di Chirurgia Generale, Ospedale Civile Sant'Andrea, La Spezia.
Minerva Chir. 1993 Oct 15;48(19):1129-33.
The authors report on a case of hepatic vein thrombosis or Budd-Chiari syndrome (BCS) successfully treated with recombinant Tissue Plasminogen Activator (rTPA). They briefly outline the etiology and symptomatology of this disease as well as the various surgical procedures used for treatment. Medical therapy has been so far poorly effective in treatment BCS, but recently various reports seem to indicate that rTPA may have a role. The authors suggest that rTPA may be used as the only therapy in selected cases, or in treating patients that are not candidates for surgical intervention, or as a temporizing measure to improve symptoms in patients awaiting surgery.
作者报告了一例用重组组织型纤溶酶原激活剂（rTPA）成功治疗肝静脉血栓形成或布加综合征（BCS）的病例。他们简要概述了该疾病的病因、症状以及用于治疗的各种外科手术。到目前为止，药物治疗在BCS治疗中效果不佳，但最近的各种报告似乎表明rTPA可能发挥作用。作者建议，rTPA可在特定病例中用作唯一治疗方法，或用于治疗不适合手术干预的患者，或作为一种临时措施来改善等待手术患者的症状。
