一种与哺乳动物II型钙/钙调蛋白依赖性蛋白激酶同源的钙/钙调蛋白结合丝氨酸/苏氨酸蛋白激酶在植物细胞中表达。
A calcium/calmodulin-binding serine/threonine protein kinase homologous to the mammalian type II calcium/calmodulin-dependent protein kinase is expressed in plant cells.
作者信息
Watillon B, Kettmann R, Boxus P, Burny A
机构信息
Faculté des Sciences Agronomiques, Unité de Biologie Moléculaire et Physiologie Animale, Gembloux, Belgium.
出版信息
Plant Physiol. 1993 Apr;101(4):1381-4. doi: 10.1104/pp.101.4.1381.
Abstract
cDNA fragments corresponding to an apple (Malus domestica [L.] Borkh) calmodulin-binding polypeptide have been isolated and characterized. The protein encoded by this messenger contains a serine/threonine protein kinase catalytic domain followed by a calcium/calmodulin-binding regulatory domain, both exhibiting significant sequence similarities to the corresponding regions of the mammalian calcium/calmodulin-dependent protein kinase II subunits. These results confirm a potential regulatory role for calmodulin in phosphorylation-mediated signal transduction events.
摘要
已经分离并鉴定了与苹果（苹果属[L.]博尔克）钙调蛋白结合多肽相对应的cDNA片段。该信使编码的蛋白质包含一个丝氨酸/苏氨酸蛋白激酶催化结构域，后面跟着一个钙/钙调蛋白结合调节结构域，两者都与哺乳动物钙/钙调蛋白依赖性蛋白激酶II亚基的相应区域表现出显著的序列相似性。这些结果证实了钙调蛋白在磷酸化介导的信号转导事件中的潜在调节作用。
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