Current nonsteroidal anti-inflammatory drug applications for rheumatic diseases.

This article reviews recent knowledge of the pharmacology of non-steroidal anti-inflammatory drugs (NSAIDs). Changes in use and perception of safety considerations are discussed. Additionally, the concept that all NSAIDs are both anti-inflammatory and analgesic is introduced, discussing the mechanism for each effect. A glimpse into the future of NSAIDs is presented, including different formulations and the concept of enantiomers and their possible role in future developments.