Magovern G J, Liebler G A, Cushing W J, Park S B, Burkholder J A
J Thorac Cardiovasc Surg. 1977 Jan;73(1):64-74.
A review of 375 cases of aortic valve replacement with the Magovern-Cromie sutureless prosthesis demonstrated a 43 per cent survival rate 10 to 13 years following the operation. Of the 308 patients surviving zero to 30 days, 238 patients are alive after one to 14 years. A total of 70 patients (22 per cent died during the 14 year follow-up period. The actuarial survival rate of all patients at risk was 64 per cent at the fifth year and 51 per cent at the tenth year. For those patients who lived at least one year after surgery, the probability of survival was 84 per cent and 70 per cent at 5 and 10 years, respectively. These results compare favorably with reports of up to only 8 years with the Smeloff-Cutter and Starr-Edwards prostheses. There was only a 1.5 per cent incidence of perivalvular leak with this method of fixation, and no valve has migrated. Ball variance has not occurred with any valve inserted since 1964, and the incidence of thromboembolism with the Model A4 prosthesis is 2.4 per cent. Improvement in results depend on reduction of thromboembolism, lessening of late and operative morality rates, and by earlier operative intervention to reduce the late deaths from cardiogenic factors.
对375例使用马戈文-克罗米无缝合人工瓣膜进行主动脉瓣置换术的病例进行回顾显示，术后10至13年的生存率为43%。在术后0至30天存活的308例患者中，238例在术后1至14年仍存活。共有70例患者（22%）在14年的随访期内死亡。所有有风险患者的精算生存率在第5年为64%，在第10年为51%。对于那些术后至少存活1年的患者，5年和10年的生存概率分别为84%和70%。这些结果与使用斯梅洛夫-卡特和斯塔尔-爱德华兹人工瓣膜的报告相比，后者最长随访时间仅8年，显示出优势。采用这种固定方法，瓣周漏的发生率仅为1.5%，且没有瓣膜移位。自1964年以来，所植入的任何瓣膜均未出现球瓣变异，A4型人工瓣膜的血栓栓塞发生率为2.4%。结果的改善取决于减少血栓栓塞、降低晚期和手术死亡率，以及通过更早的手术干预减少心源性因素导致的晚期死亡。
