Potter J F, Fotherby M D, Macdonald I A
University Department of Medicine for the Elderly, Leicester General Hospital.
Age Ageing. 1993 Nov;22(6):404-10. doi: 10.1093/ageing/22.6.404.
Little work has been conducted to assess repeatability and relation of arterialized plasma catecholamines to blood pressure in elderly subjects. We studied 19 untreated elderly patients with essential hypertension and 19 matched normotensives on two occasions one week apart. After prolonged supine rest, BP, pulse rate and arterialized plasma catecholamine levels were measured. Systolic (SBP) and diastolic (DBP) blood pressure, plasma adrenaline (A) and noradrenaline (NA) repeatabilities were similar for the hypertensive and normotensive groups. Mean supine pulse rate was significantly higher in the hypertensive group as were arterialized plasma A, but not NA, levels. For the whole group there was a significant univariate correlation between log plasma A and SBP (r = 0.53), DBP (r = 0.59) and pulse rate (r = 0.41). In keeping with previously published work in younger subjects these results indicate a possible role for adrenaline in the maintenance of raised blood pressure levels in elderly people.
在老年受试者中，评估动脉化血浆儿茶酚胺与血压的重复性及关系的研究工作较少。我们对19例未经治疗的老年原发性高血压患者和19例匹配的血压正常者进行了研究，两次测量间隔一周。经过长时间仰卧休息后，测量血压、脉搏率和动脉化血浆儿茶酚胺水平。高血压组和血压正常组的收缩压（SBP）和舒张压（DBP）、血浆肾上腺素（A）和去甲肾上腺素（NA）的重复性相似。高血压组的平均仰卧脉搏率显著更高，动脉化血浆A水平也是如此，但NA水平并非如此。对于整个组，血浆A的对数与SBP（r = 0.53）、DBP（r = 0.59）和脉搏率（r = 0.41）之间存在显著的单变量相关性。与之前在年轻受试者中发表的研究结果一致，这些结果表明肾上腺素在维持老年人血压升高方面可能发挥作用。
