Ramirez F, Salazar S, Madurga B, Ibañez R, Baez Perea J M, Flores Gines J
Hospital Universitario Puerta del Mar, Cádiz, España.
Arch Esp Urol. 1993 Oct;46(8):735-7.
A case of complete testicular feminization (Morris syndrome) in a male pseudohermaphrodite is described. The results of the hormone analyses and the histological features of the resected gonad are presented. The literature is reviewed with special reference to whether gonadectomy should be performed in the pre or post-pubertal period. We advocate early castration because of the high incidence of germ cell neoplasia and the possibility of virilization in case of incomplete androgenic resistance. Our approach is based on the satisfactory feminization achieved by exogenous estrogen therapy.
本文描述了一例男性假两性畸形中的完全性睾丸女性化(莫里斯综合征)病例。文中呈现了激素分析结果以及切除性腺的组织学特征。回顾了相关文献,特别提及性腺切除术应在青春期前还是青春期后进行。由于生殖细胞肿瘤的高发病率以及不完全雄激素抵抗情况下出现男性化的可能性,我们主张早期去势。我们的方法基于外源性雌激素治疗所实现的令人满意的女性化效果。