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[气体性缺氧时肾脏辐射损伤的组织化学与生物化学研究]

[Histochemical and biochemical study of radiation injury of the kidneys in gas hypoxia].

作者信息

Ostrovskaia S S, Ostapenko V V, Slesarenko E G, Waĭnson A A, Raĭkhlin N T

出版信息

Arkh Patol. 1993;55(4):72-4.

PMID:8311718
Abstract

A radioprotective effect of hypoxia was studied in kidney radiation. The use of hypoxic respiratory mixture containing 8% oxygen (the normal content is 21%) enhances kidney resistance to local single and fractionated irradiation. Determination of renal activity of succinate dehydrogenase, lactate dehydrogenase, acid and alkaline phosphatase and urinary N-acetyl-beta-D-glucosaminidase, gamma-glutamyl transferase, alkaline phosphatase, lactate dehydrogenase is recommended as tests for kidney radiation damage.

摘要

在肾脏辐射中研究了缺氧的辐射防护作用。使用含8%氧气(正常含量为21%)的低氧呼吸混合气可增强肾脏对局部单次和分次照射的抵抗力。推荐测定琥珀酸脱氢酶、乳酸脱氢酶、酸性和碱性磷酸酶的肾脏活性以及尿N-乙酰-β-D-氨基葡萄糖苷酶、γ-谷氨酰转移酶、碱性磷酸酶、乳酸脱氢酶,作为肾脏辐射损伤的检测指标。

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