Goldstein S M
Department of Dermatology, University of California, San Francisco 94143-0536.
Semin Dermatol. 1993 Dec;12(4):315-30.
This article reviews recent controlled studies of treatment for candida infections of the skin and mucous membranes. In general, excellent agents are available for treatment, with reasonable alternatives for the uncommon emergence of resistant strains. Cutaneous infections in immunocompetent patients are effectively treated with topical agents. The major clinical problems that remain include frequently recurrent vulvovaginal candidiasis, and oroesophageal candida infections in patients with malignancies and immunosuppression. These often require systemic therapy. A number of treatment strategies have been investigated and are reviewed.
本文综述了近期关于皮肤和黏膜念珠菌感染治疗的对照研究。总体而言，有优秀的药物可用于治疗，对于耐药菌株罕见出现的情况也有合理的替代方案。免疫功能正常患者的皮肤感染可通过局部用药有效治疗。仍然存在的主要临床问题包括复发性外阴阴道念珠菌病，以及恶性肿瘤和免疫抑制患者的口腔食管念珠菌感染。这些情况通常需要全身治疗。已经研究并综述了多种治疗策略。
