Huang C J, Lee M S, Chang G D, Huang F L, Lo T B
Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan, ROC.
Biochim Biophys Acta. 1994 Jan 13;1220(2):223-5. doi: 10.1016/0167-4889(94)90140-6.
We have cloned a full-length cDNA encoding the mitogen-activated protein kinase kinase (MKK) from a carp liver cDNA library. The cDNA contains 1970 bp with a single open reading frame encoding a 397 amino acid protein. By comparing with known MKK sequences from other species, carp MKK is 78%, 80%, 76% and 58% identical to rat MKK1, rat MKK2, Xenopus MKK and Drosophila MKK.