Yasuda M, Loo M, Shiokawa S, Wada T, Suenaga Y, Nobunaga M
Department of Clinical Immunology, Kyushu University, Oita, Japan.
Intern Med. 1993 Aug;32(8):633-7. doi: 10.2169/internalmedicine.32.633.
We herein describe a 41-year-old female patient with an association of myasthenia gravis (MG) with anti-acetylcholine receptor (AcR) antibody, mixed connective tissue disease (MCTD) and Sjögren's syndrome (SjS). We reviewed the reported association of MG and MCTD, systemic lupus erythematosus, progressive systemic sclerosis, polymyositis and dermatomyositis, and SjS. Since we could find only two patients who fulfilled the diagnostic criteria for MCTD in the previous literature, we concluded that the association of MG and MCTD is rare. We also discuss the coexistence of SjS as one of the underlying pathological conditions for the association of MG and various connective tissue diseases including MCTD.
我们在此描述一名41岁女性患者，患有抗乙酰胆碱受体（AcR）抗体阳性的重症肌无力（MG）、混合性结缔组织病（MCTD）和干燥综合征（SjS）。我们回顾了已报道的MG与MCTD、系统性红斑狼疮、进行性系统性硬化症、多发性肌炎和皮肌炎以及SjS的关联。由于我们在以往文献中仅能找到两名符合MCTD诊断标准的患者，我们得出结论，MG与MCTD的关联较为罕见。我们还讨论了SjS作为MG与包括MCTD在内的各种结缔组织病关联的潜在病理状况之一的共存情况。
