Vinogradova L F, Mirzoian Zh A
Eksp Klin Farmakol. 1993 Sep-Oct;56(5):50-2.
The effects of the anthelmintic agent chloxyl given to rabbits in different doses were compared with those of CCl4 on the excretory function of the liver. There was a similarity of the above agents in their inhibitory effects on hepatic excretory function. The hepatoprotective effect of the antioxidant sodium selenite was found to be more pronounced than that of vitamin E. The combination of the above antioxidants was most effective in normalizing the excretory function of the liver affected by CCl4 and chloxyl, revealing the potentiation of their effect.
将不同剂量的驱虫剂氯羟喹给兔子服用，并将其对肝脏排泄功能的影响与四氯化碳的影响进行比较。上述药物对肝脏排泄功能的抑制作用具有相似性。发现抗氧化剂亚硒酸钠的肝保护作用比维生素E更显著。上述抗氧化剂联合使用对受四氯化碳和氯羟喹影响的肝脏排泄功能恢复正常最为有效，显示出其作用的增强。
