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脑室内注射α干扰素治疗拉斯穆森综合征。

Intraventricular alpha interferon therapy for Rasmussen's syndrome.

作者信息

Maria B L, Ringdahl D M, Mickle J P, Smith L J, Reuman P D, Gilmore R L, Drane W E, Quisling R G

机构信息

Division of Pediatric Neurology, University of Florida College of Medicine, Gainesville 32610-0296.

出版信息

Can J Neurol Sci. 1993 Nov;20(4):333-6.

PMID:8313251
Abstract

A 4-year-old boy developed Rasmussen's syndrome and was treated with alpha interferon intraventricularly. An improvement in the epileptic and neurologic syndrome was noted for several weeks following interferon. No adverse side effects were encountered. Since hemispherectomy is the only established therapy in Rasmussen's Syndrome, further studies are needed to establish if intraventricular alpha interferon may halt the clinical progression of the syndrome.

摘要

一名4岁男孩患上了拉斯姆森综合征,并接受了脑室内注射α干扰素的治疗。注射干扰素后的几周内,癫痫和神经综合征有了改善。未出现不良副作用。由于大脑半球切除术是拉斯姆森综合征唯一已确立的治疗方法,因此需要进一步研究以确定脑室内注射α干扰素是否可以阻止该综合征的临床进展。

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引用本文的文献

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Rasmussen Encephalitis: Clinical Features, Pathophysiology, and Management Strategies-A Comprehensive Literature Review.拉森姆脑炎:临床特征、病理生理学和管理策略——全面文献综述。
Medicina (Kaunas). 2024 Nov 12;60(11):1858. doi: 10.3390/medicina60111858.
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Rasmussen's encephalitis presenting as focal cortical dysplasia.表现为局灶性皮质发育异常的拉斯穆森脑炎。
Epilepsy Behav Case Rep. 2014 Mar 12;2:86-9. doi: 10.1016/j.ebcr.2014.01.009. eCollection 2014.
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Dual Pathology in Rasmussen's Encephalitis: A Report of Coexistent Focal Cortical Dysplasia and Review of the Literature.
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Case Rep Pathol. 2012;2012:569170. doi: 10.1155/2012/569170. Epub 2012 Sep 29.
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Autoimmune encephalitis in children.儿童自身免疫性脑炎
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Rasmussen's Encephalitis.拉斯穆森脑炎
Curr Treat Options Neurol. 2001 Nov;3(6):555-563. doi: 10.1007/s11940-001-0018-5.
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Rasmussen's syndrome: pathogenetic theories and therapeutic strategies.拉斯穆森综合征:发病机制理论与治疗策略。
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