Furr M, Taylor L, Kronfeld D
Marion duPont Scott Equine Center, Virginia-Maryland Regional College of Veterinary Medicine, Lessburg 22075.
Cornell Vet. 1994 Jan;84(1):41-5.
Gastroendoscopic surveys have shown that horses in race training have a greater prevalence of gastric ulceration than sedentary horses. To determine if exercise affects gastric endocrine function the following experiment was performed. Four horses were fed total mixed ration of ground corn and chopped hay at 2% of their body weight, divided into 2 equal portions, daily. Horses were fasted overnight, and serum gastrin concentration was determined just before and 2 hours after feeding. The horses were then sprint trained on a high speed treadmill for 6 weeks. The response of serum gastrin to feeding was then repeated as before. Serum gastrin increased following feeding both before and after training, however the postfeeding gastrin value was higher [p = 0.035] after training (68.1 +/- 6.9 pg/ml [mean +/- 1 SEM]) than before (42.7 +/- 3.8 pg/ml). These data show that treadmill exercise has an effect upon the gastric hormonal response to a meal in the horse. The relationship of this finding to the development of gastric ulcer disease is unknown at present, but warrants further investigation.
胃肠内镜检查显示，参加赛马训练的马匹胃溃疡的患病率高于非运动马匹。为了确定运动是否会影响胃内分泌功能，进行了以下实验。给4匹马每天喂食按体重2%计算的玉米粉和切碎干草的全混合日粮，并分成两份等量投喂。马匹禁食过夜，在喂食前和喂食后2小时测定血清胃泌素浓度。然后让这些马在高速跑步机上进行短跑训练6周。之后像之前一样再次测定血清胃泌素对喂食的反应。训练前后喂食后血清胃泌素均升高，然而训练后（68.1±6.9皮克/毫升[平均值±1标准误]）的喂食后胃泌素值高于训练前（42.7±3.8皮克/毫升）[p = 0.035]。这些数据表明，跑步机运动对马进食后的胃激素反应有影响。目前尚不清楚这一发现与胃溃疡疾病发展之间的关系，但值得进一步研究。
