Fergestad Marte Ekeland, Jahr Tuva Holt, Krontveit Randi I, Skancke Ellen
Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine and Biosciences, Norwegian University of Life Sciences, PO Box 8146 Dep, 0033, Oslo, Norway.
Department of Food Safety and Infection Biology, Faculty of Veterinary Medicine and Biosciences, Norwegian University of Life Sciences, PO Box 8146 Dep, 0033, Oslo, Norway.
Acta Vet Scand. 2016 Apr 26;58:24. doi: 10.1186/s13028-016-0204-9.
High incidences of gastritis and gastric ulceration are observed in sled dogs participating in endurance races. Exercise-induced increases in hormones like gastrin and cortisol have been suggested as possible contributing factors. An increase in C-reactive protein (CRP) has also been observed in canines during physical exercise. The aim of this study was to evaluate the effect of long distance racing on the serum concentration of gastrin, cortisol and CRP in a group of sled dogs, by comparing the results achieved early in the training season and after participating in a long distance race; "Femundløpet". Dogs that only trained to the race, but did not compete in the race, were used as control dogs. Sixty-five sled dogs participated in the study; 46 competing dogs (25 completing and 21 non-completing the race) and 19 non-racing dogs (control dogs). The blood samples were collected in October 2012 and February 2013.
The post-race serum concentration of gastrin, cortisol and CRP was significantly elevated in sled dogs participating in the race (both completing and non-completing dogs) when compared to the results from training. However, no significant differences were observed between the two sampling dates in the control dogs. Post-race results for completing and non-completing dogs were also compared. This demonstrated a significant elevation in gastrin in non-completing versus completing dogs, and a significant elevation in cortisol in completing compared to non-completing dogs.
Participation in a long distance race was associated with a significant increase in serum gastrin, cortisol and CRP in sled dogs.
在参加耐力赛的雪橇犬中，胃炎和胃溃疡的发病率很高。运动引起的胃泌素和皮质醇等激素增加被认为是可能的促成因素。在犬类进行体育锻炼期间，还观察到C反应蛋白（CRP）增加。本研究的目的是通过比较训练季节早期和参加长距离比赛“费蒙德洛佩特”之后的结果，评估长距离比赛对一组雪橇犬血清胃泌素、皮质醇和CRP浓度的影响。只参加比赛训练但未参赛的犬作为对照犬。65只雪橇犬参与了该研究；46只参赛犬（25只完成比赛和21只未完成比赛）和19只非参赛犬（对照犬）。血液样本于2012年10月和2013年2月采集。
与训练结果相比，参加比赛的雪橇犬（包括完成比赛和未完成比赛的犬）赛后血清胃泌素、皮质醇和CRP浓度显著升高。然而，对照犬在两个采样日期之间未观察到显著差异。还比较了完成比赛和未完成比赛犬的赛后结果。这表明未完成比赛的犬与完成比赛的犬相比，胃泌素显著升高，而完成比赛的犬与未完成比赛的犬相比，皮质醇显著升高。
参加长距离比赛与雪橇犬血清胃泌素、皮质醇和CRP显著增加有关。
