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葡萄糖酸钙静脉滴注治疗磷烧伤

[Intravenous drop of calcium gluconate for phosphorus burns].

作者信息

Hu A J

机构信息

251 Hospital, People's Liberation Army, Zhangjiakou.

出版信息

Zhonghua Wai Ke Za Zhi. 1993 Jul;31(7):421-4.

PMID:8313772
Abstract

20 patients with phosphor burn (TBSA 2%-75%) were cured by i.v. drop of calcium gluconate combined with other therapies including eschar conservation. Our experimental data showed that dogs with burn by spreading 85% phosphoric acid and napalm locally increased the level of plasma phosphorus and pathological damages to the heart, lung, kidney and etc were similar to those previously reported phosphorus burns. Intravenous drop of calcium gluconate after phosphate burn reduced the level of plasma phosphorus to normal rapidly and lessened the visceral damages. We consider that i.v. drop of calcium gluconate can accelerate the elimination of phosphorus, and prevent phosphorus poisoning after phosphorus burns.

摘要

20例磷烧伤患者(烧伤面积占总体表面积的2%-75%)通过静脉滴注葡萄糖酸钙并结合包括保痂在内的其他疗法得以治愈。我们的实验数据表明,局部涂抹85%磷酸和凝固汽油烧伤的犬血浆磷水平升高,心脏、肺、肾等的病理损伤与先前报道的磷烧伤相似。磷烧伤后静脉滴注葡萄糖酸钙可迅速使血浆磷水平降至正常,并减轻内脏损伤。我们认为静脉滴注葡萄糖酸钙可加速磷的清除,并预防磷烧伤后磷中毒。

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1
[Intravenous drop of calcium gluconate for phosphorus burns].葡萄糖酸钙静脉滴注治疗磷烧伤
Zhonghua Wai Ke Za Zhi. 1993 Jul;31(7):421-4.
2
[Therapeutic effect of calcium preparation in phosphorus poisoning following phosphorus burns].钙制剂对磷烧伤后磷中毒的治疗作用
Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi. 1993 Jul;9(4):254-6, 317-8.
3
[The mechanism of hemorrhage following phosphorus burns and the effect of calcium gluconate].[磷烧伤后出血的机制及葡萄糖酸钙的作用]
Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi. 1998 Jan;14(1):45-8.
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The clinical effectiveness of the intravenous infusion of calcium gluconate for treatment of hydrofluoric acid burn of distal limbs.静脉输注葡萄糖酸钙治疗四肢远端氢氟酸烧伤的临床疗效。
Burns. 2014 Jun;40(4):e26-30. doi: 10.1016/j.burns.2013.12.003. Epub 2014 Jan 10.
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[Comparison of various methods of early management of hydrofluoric acid burn in rabbits].[兔氢氟酸烧伤早期处理各种方法的比较]
Zhonghua Shao Shang Za Zhi. 2005 Feb;21(1):40-2.
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7 cases of hydrofluoric acid burn in which calcium gluconate was effective for relief of severe pain.7例氢氟酸烧伤患者,葡萄糖酸钙对其严重疼痛缓解有效。
Contact Dermatitis. 2005 Mar;52(3):133-7. doi: 10.1111/j.0105-1873.2005.00521.x.
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Intravenous regional calcium gluconate perfusion for hydrofluoric acid burns.
J Toxicol Clin Toxicol. 1992;30(2):203-7. doi: 10.3109/15563659209038631.
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Failure of intravenous calcium gluconate for hydrofluoric acid burns.
Ann Emerg Med. 2000 Oct;36(4):398. doi: 10.1067/mem.2000.110019.
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Hydrofluoric acid dermal burns. An assessment of treatment efficacy using an experimental pig model.氢氟酸皮肤烧伤。使用实验性猪模型评估治疗效果。
J Occup Med. 1992 Sep;34(9):902-9.
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[A patient with a subungual burn caused by hydrofluoric acid].[一名因氢氟酸导致甲下烧伤的患者]
Ned Tijdschr Geneeskd. 1986 Feb 15;130(7):322.

引用本文的文献

1
White phosphorus munitions: pathophysiology, clinical management, and multidisciplinary perspectives on burn injuries and humanitarian challenges.白磷弹药:烧伤的病理生理学、临床管理以及关于烧伤伤害和人道主义挑战的多学科观点。
Front Public Health. 2025 Jul 25;13:1632840. doi: 10.3389/fpubh.2025.1632840. eCollection 2025.