Exum M E, Phelps B J, Nabers K E, Osborne J G
Department of Psychology, Utah State University, Logan 84322-2810.
Gerontologist. 1993 Dec;33(6):756-61. doi: 10.1093/geront/33.6.756.
Sundown syndrome describes the increase in agitation and delirium in elderly patients with dementia that occurs in the evening after sunset. In a nursing home, data were gathered over a year-long period to test the hypothesis that the administration of PRN (pro re nata, given as needed) medications for agitation in Alzheimer's patients would reflect sundown syndrome. More PRNs were administered in the early morning and mid-afternoon hours than at other times of the day. These outcomes suggest there is a relationship of PRN use for agitation, in institutionalized Alzheimer's patients, to environmental variables other than sunset.
日落综合征是指老年痴呆患者在日落后的傍晚出现的躁动和谵妄加重的情况。在一家养老院,研究人员收集了长达一年的数据,以检验以下假设:按需给阿尔茨海默病患者使用(必要时)PRN(拉丁语,意为必要时给予)药物治疗躁动,这一情况是否反映了日落综合征。清晨和下午中段时段使用的PRN药物比一天中的其他时段更多。这些结果表明,在机构化的阿尔茨海默病患者中,使用PRN药物治疗躁动与日落以外的环境变量有关。