Büchi E R, Schiller P, Felice M, Bunkenburg A, Daicker B
University Eye Hospital, Basel, Switzerland.
Int Ophthalmol. 1993 Feb;17(1):37-42. doi: 10.1007/BF00918866.
The physiology of the orbital arteries supplying the eye is currently under intensive investigation. However, while the anatomical distribution of these vessels in humans is well known, their normal histology and age-related or other pathologic alterations have hardly been studied. We obtained at autopsy 10 orbits from persons aged > or = 74 years, and two orbits from a person aged 47 years. Specimens were taken from 20 locations along the orbital arteries, from the internal carotid to the globe, and studied by light microscopy. We observed the following arteriosclerotic changes, in order of decreasing frequency: intimal hyperplasia, medial atrophy, atherosclerotic fibrous plaques, and calcifications of the internal elastic lamina. As a rule, the intensity of the changes decreased from proximal to distal. This study shows that aged human orbital arteries are readily subject to degenerative changes that may play an important role in ophthalmic vascular disease.
目前，为眼睛供血的眼眶动脉的生理学正处于深入研究阶段。然而，虽然这些血管在人体中的解剖分布已为人熟知，但其正常组织学以及与年龄相关的或其他病理改变却几乎未被研究过。我们在尸检时获取了10个年龄≥74岁者的眼眶，以及1个47岁者的2个眼眶。沿着眼眶动脉从颈内动脉至眼球选取20个部位的标本，进行光学显微镜检查。我们观察到以下动脉硬化改变，按出现频率递减依次为：内膜增生、中膜萎缩、动脉粥样硬化纤维斑块以及内弹性膜钙化。通常，这些改变的强度从近端到远端逐渐减弱。本研究表明，老年人眼眶动脉容易发生退行性改变，这可能在眼科血管疾病中起重要作用。
