妊娠期糖尿病患者羊水中的葡萄糖

Amniotic fluid glucose in pregnancies complicated by diabetes.

作者信息

Cassady G, Blake M, Bailey P, Younger B, Sumners J

出版信息

Am J Obstet Gynecol. 1977 Jan 1;127(1):21-5. doi: 10.1016/0002-9378(77)90308-8.

Abstract

Amniotic fluid glucose (AF glu) was studied in 92 pregnancies complicated by maternal diabetes. An inverse relation between AF glu and gestational age was found: [AF glu (mg. per diciliter) = 160.9 -- 3.51 (weeks gestation); r = -0.47]. A direct relation between AF glu and severity of maternal diabetes was observed: mean AF glu (mg. per deciliter) = 24.6 +/- S.D. 12.3 in Class A, 41.2 +/- 25.5 in Class AD and 57.5 +/- 36.5 in Classes B-D. A positive correlation of AF glu with osmolality was observed [AF Osm (mOsm. per kilogram) = 250.7 + 0.22 AF glu; r = +0.50], but this relation was remarkable inconsistent in individual patients. Neither individual nor serial AF glu levels were of any prognostic value in predicting fetal condition or perinatal outcome.

摘要

对92例合并母体糖尿病的妊娠病例的羊水葡萄糖（AF glu）进行了研究。发现AF glu与孕周呈负相关：[AF glu（毫克/分升）= 160.9 - 3.51（孕周）；r = -0.47]。观察到AF glu与母体糖尿病严重程度呈正相关：A类患者平均AF glu（毫克/分升）= 24.6 ±标准差12.3，AD类为41.2 ± 25.5，B - D类为57.5 ± 36.5。观察到AF glu与渗透压呈正相关[AF Osm（毫摩尔/千克）= 250.7 + 0.22 AF glu；r = +0.50]，但这种关系在个体患者中明显不一致。个体或连续的AF glu水平在预测胎儿状况或围产期结局方面均无任何预后价值。