Obana M, Hanada T, Ohta S, Matsuoka Y, Irimajiri S, Fukuda J
Department of Internal Medicine and Pathology, Kawasaki Municipal Hospital.
Kansenshogaku Zasshi. 1993 Apr;67(4):349-54. doi: 10.11150/kansenshogakuzasshi1970.67.349.
A 62-year-old woman, who had been diagnosed as having rheumatoid arthritis (RA) with systemic amyloidosis and diabetes mellitus, was admitted to our hospital because of polyarthralgia on October 1, 1987. She had some subcutaneous nodules and rheumatic pleural effusion. Therefore she was treated with 20 milligrams of prednisolone (PSL) daily. On the ninth day after the beginning of steroid therapy, she complained of severe pain and a new swelling in her right knee joint. The knee joint aspirate on arthrocentesis yielded a pure growth of group B Streptococcus (GBS). Blood culture was also positive for GBS. Her suppurative arthritis gradually improved by treatment with penicillin G. However, after the discontinuance of PSL, her pleural effusion deteriorated and she died on January 10, 1988. To our knowledge, there have been no prior reports of group B streptococcal suppurative arthritis complicating RA in Japan.
一名62岁女性，被诊断为患有类风湿关节炎（RA）并伴有系统性淀粉样变性和糖尿病，因多关节疼痛于1987年10月1日入住我院。她有一些皮下结节和风湿性胸腔积液。因此，她每天接受20毫克泼尼松龙（PSL）治疗。在开始使用类固醇治疗后的第九天，她抱怨右膝关节剧痛并出现新的肿胀。关节穿刺抽取的膝关节积液培养出纯的B组链球菌（GBS）。血培养GBS也呈阳性。通过青霉素G治疗，她的化脓性关节炎逐渐好转。然而，停用PSL后，她的胸腔积液恶化，于1988年1月10日死亡。据我们所知，日本此前尚无B组链球菌化脓性关节炎并发RA的报道。
