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Severe phenytoin-induced bone marrow depression and agranulocytosis treated with human recombinant granulocyte-macrophage colony-stimulating factor. Case report.

作者信息

Rawanduzy A, Sarkis A, Rovit R L

机构信息

Department of Neurological Surgery, St. Vincent's Hospital and Medical Center of New York, New York.

出版信息

J Neurosurg. 1993 Jul;79(1):121-4. doi: 10.3171/jns.1993.79.1.0121.

DOI:10.3171/jns.1993.79.1.0121
PMID:8315450
Abstract

An unusual instance of severe and potentially lethal depression of the bone marrow is described as a result of the administration of phenytoin for seizure prophylaxis. The patient was treated successfully by prompt cessation of phenytoin and intravenous administration of human recombinant granulocyte-macrophage colony-stimulating factor.

摘要

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