Weinstein S P, Gottheil E, Sterling R C, DeMaria P A
Department of Psychiatry and Human Behavior, Thomas Jefferson University, Jefferson Medical College, Philadelphia, Pennsylvania 19107.
J Subst Abuse Treat. 1993 May-Jun;10(3):277-81. doi: 10.1016/0740-5472(93)90075-d.
After 27 years methadone maintenance remains perhaps the most controversial form of available opiate addiction treatment. Recognizing that many patients choose to remain in methadone treatment for extended periods of time the authors have wondered whether such patients might actually be harmed by long-term involvement. A review of the records of 3 patients who had been in continuous treatment for 15 years or more revealed that all of their lives had improved over the course of their treatment involvement. They varied in the length of time required before they showed improvement and all three indicated that they wished to remain on methadone because previously they had resumed drug use when they tried detoxing either alone or in treatment. There were periods during their treatment involvement when these patients were not doing well and could have been regarded as treatment failures. Continuing on in treatment, however, all three had made positive changes in their lives, changes which were of benefit to the society as well as the individual.
27年来,美沙酮维持治疗可能仍是现有的阿片类药物成瘾治疗中最具争议性的形式。鉴于许多患者选择长期接受美沙酮治疗,作者们不禁思考,长期接受治疗的患者是否实际上会受到伤害。回顾3名持续治疗15年或更长时间的患者记录发现,在整个治疗期间,他们的生活都有改善。他们在出现改善之前所需的时间长度各不相同,三人都表示希望继续服用美沙酮,因为之前他们单独尝试戒毒或在治疗中戒毒时又恢复了吸毒。在他们接受治疗期间,有一段时间这些患者情况不佳,可能被视为治疗失败。然而,继续接受治疗后,三人都在生活中做出了积极改变,这些改变对社会和个人都有益处。