Tani K, Bando M
Department of Respiratory Disease, Miyoshi Hospital, Tokushima, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1993 Mar;31(3):341-5.
To investigate the clinical course of patients with silicosis receiving home oxygen therapy (HOT), we compared the clinical data of HOT patients with silicosis and those with other respiratory diseases, and of silicotic patients with HOT and those without HOT in our hospital. In 23 (34.3%) of 68 patients receiving HOT the underlying disease was silicosis. This figure differs from recent official statistics in Japan. In the patients with silicosis, the survival rate was lower than that of those with chronic obstructive pulmonary diseases or old pulmonary tuberculosis, but the degree of decrease in PaO2 was smaller, suggesting that the prognosis of silicotic patients may be mainly related to pulmonary hypertension and cor pulmonale. In silicotic patients, large opacities on chest X-ray were frequently observed in the patients with HOT compared to those without HOT, indicating that the presence of large opacities is an important factor influencing hypoxemia in silicotic patients.
为了研究接受家庭氧疗（HOT）的矽肺患者的临床病程，我们比较了我院接受HOT的矽肺患者与其他呼吸系统疾病患者的临床数据，以及接受HOT和未接受HOT的矽肺患者的临床数据。在68例接受HOT的患者中，有23例（34.3%）的基础疾病为矽肺。这一数字与日本最近的官方统计数据有所不同。在矽肺患者中，其生存率低于慢性阻塞性肺疾病或陈旧性肺结核患者，但动脉血氧分压（PaO2）的下降程度较小，这表明矽肺患者的预后可能主要与肺动脉高压和肺心病有关。在矽肺患者中，与未接受HOT的患者相比，接受HOT的患者胸部X线片上经常出现大阴影，这表明大阴影的存在是影响矽肺患者低氧血症的一个重要因素。
