Nakamura A, Yamada Y, Yamamoto T, Yamamoto K, Takeuchi T
First Department of Internal Medicine, Nagoya City University, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1993 Mar;31(3):394-8.
A case is reported of osteosarcoma of the 11th rib in a 38-year-old woman who presented with dry cough and dyspnea due to bloody pleural effusion and the literature on osteosarcoma of the rib in Japan is reviewed. Osteosarcoma was suggested by roentgenologic findings and examination of a percutaneous needle biopsy specimen. Therefore, we administered chemotherapy, but the tumor showed progressive expansion and invasion, causing paraplegia. The patient died on the 282nd day of admission. We performed an autopsy and diagnosed osteosarcoma histologically. The tumor was covered by a hypervascular capsule, suggesting its association with the bloody pleural effusion. Osteosarcoma of the rib has not been previously reported in association with bloody pleural effusion. Considering the prognosis and characteristics of such tumors, we recommend prompt diagnosis in cases presenting with bloody pleural effusion.
报告了一例38岁女性第11肋骨骨肉瘤病例，该患者因血性胸腔积液出现干咳和呼吸困难，并对日本肋骨骨肉瘤的文献进行了综述。X线检查结果及经皮针吸活检标本检查提示骨肉瘤。因此，我们给予了化疗，但肿瘤仍呈进行性扩大和侵袭，导致截瘫。患者在入院第282天死亡。我们进行了尸检并从组织学上诊断为骨肉瘤。肿瘤被富含血管的包膜覆盖，提示其与血性胸腔积液有关。此前尚未有肋骨骨肉瘤与血性胸腔积液相关的报道。考虑到此类肿瘤的预后和特征，我们建议对出现血性胸腔积液的病例进行及时诊断。
