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[部分接种疫苗人群中四次麻疹暴发期间的传播情况]

[Transmission of measles during four outbreaks in a partially vaccinated population].

作者信息

Grilli G, Cimini D, Morbidelli L, Vacca F

机构信息

Servizio di Igiene e Sanità Pubblica, USL n. 10, Marche, Jesi, Ancona.

出版信息

Minerva Pediatr. 1993 Jan-Feb;45(1-2):21-8.

PMID:8316159
Abstract

All measles cases occurred between 1989 and 1991 in the territory of the Local Health Unit 10--Marche Region--Italy, were studied in order to evaluate the characteristics of the disease and the transmission mechanisms. A total of 4 outbreaks were evidenced: 2 occurred in a 40,000 population municipality (with 46 and 87 cases, respectively), 1 in a 10,000 population municipality (with 35 cases) and 1 in two closely-related municipalities of 4,600 population (with 67 cases). The immune status of children between 1 and 10 years of age was evaluated adding the number of vaccinated children to the number of those who resulted having had the disease. Immune children were between 52.3% and 89.1%. During the outbreaks, the percentage of cases occurred in subjects over 10 years of age was, in total, 65.5. No cases needed hospitalization and only one case occurred in a vaccinated boy. In 189 cases the subject who presumably transmitted the disease was identified. Transmission occurred: within the school in 51.8% of the cases; within the family in 30.7%; during social activity in 10.0%; from inhabitants of the same house in 7.4%. The epidemiology of measles, in the area of this study, seems different from that described in the United States.

摘要

对意大利马尔凯大区第10地方卫生单位辖区内1989年至1991年期间发生的所有麻疹病例进行了研究,以评估该疾病的特征和传播机制。共发现4起疫情:2起发生在一个有4万人口的市镇(分别有46例和87例),1起发生在一个有1万人口的市镇(有35例),1起发生在两个关系密切、有4600人口的市镇(有67例)。通过将接种疫苗儿童的数量与确诊患过该病的儿童数量相加,评估了1至10岁儿童的免疫状况。免疫儿童占52.3%至89.1%。在疫情期间,10岁以上人群中的病例占比总计为65.5%。没有病例需要住院治疗,只有1例发生在一名接种过疫苗的男孩身上。在189例病例中,确定了可能传播疾病的人。传播途径如下:51.8%的病例发生在学校内;30.7%发生在家庭内;10.0%发生在社交活动期间;7.4%发生在同一房屋的居住者之间。在本研究区域,麻疹的流行病学情况似乎与美国描述的不同。

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