Chassagne D, Sismondi P, Horiot J C, Sinistrero G, Bey P, Zola P, Pernot M, Gerbaulet A, Kunkler I, Michel G
Tumor Institute, Institut Gustave-Roussy, Villejuif, France.
Radiother Oncol. 1993 Mar;26(3):195-202. doi: 10.1016/0167-8140(93)90260-f.
Reporting and scoring treatment complications in gynecological cancers is difficult because of the variety of normal tissues, anatomical structures and treatment disciplines involved, making it impossible to compare series of patients treated in different institutions even with the same strategy. An international group of experts (gynecologists, radiotherapists and surgeons) developed a multidisciplinary database to identify, score and report early and late normal tissue damage regardless of treatment strategy. The principles involve: (1) The identification of relevant organs and tissues; (2) An accurate definition of the type and score of each complication; (3) Reporting combinations of complications of various degrees; (4) A computerized format for data acquisition, update and retrieval. In the present version, the "Glossary" describes five degrees of increasing severity (0 to 4) in 14 organs and/or normal tissues. The rationale of the glossary leaves it open for as yet undescribed types of complications. This paper contains the definition and scoring for each type of complication, general guidelines for their use.
由于涉及多种正常组织、解剖结构和治疗学科，报告和评分妇科癌症的治疗并发症很困难，这使得即使采用相同策略，也无法比较不同机构治疗的患者系列。一个国际专家小组（妇科医生、放射治疗师和外科医生）开发了一个多学科数据库，以识别、评分和报告早期和晚期正常组织损伤，而不考虑治疗策略。其原则包括：（1）识别相关器官和组织；（2）准确界定每种并发症的类型和评分；（3）报告不同程度并发症的组合；（4）采用计算机化格式进行数据采集、更新和检索。在当前版本中，“术语表”描述了14个器官和/或正常组织中严重程度逐渐增加的五个等级（0至4）。该术语表的基本原理为尚未描述的并发症类型留出了空间。本文包含每种并发症类型的定义和评分及其使用的一般指南。
