Kotake T, Miura N, Ito H
Department of Urology, Teikyo University School of Medicine, Ichihara Hospital, Chiba, Japan.
Scanning Microsc. 1993 Mar;7(1):417-21.
The information concerning the relationship of hypouricemia with urinary tract stones is limited. We investigated the incidence and types of hypouricemia, and also studied its relationship to urinary tract stones. Hypouricemia was detected in 3 out of 1520 outpatients (0.20%). The loading tests using pyrazinamide, probenecid and benzbromarone showed that uric acid absorption was impaired before tubular secretion in two cases and incomplete postsecretory reabsorption in one case. Complication of urinary tract stone was found in two cases. The composition of the stones was mixed calcium oxalate and uric acid. Hypouricemia should be recognized as one of the causes of kidney stone formation.
关于低尿酸血症与尿路结石关系的信息有限。我们调查了低尿酸血症的发生率和类型，并研究了其与尿路结石的关系。在1520名门诊患者中有3例检测到低尿酸血症（0.20%）。使用吡嗪酰胺、丙磺舒和苯溴马隆的负荷试验表明，2例患者在肾小管分泌前尿酸吸收受损，1例患者分泌后重吸收不完全。发现2例并发尿路结石。结石成分是草酸钙和尿酸混合。低尿酸血症应被视为肾结石形成的原因之一。
